Botulinum Toxin A for Hyperhidrosis (Excessive Sweating)

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Hyperhidrosis is a condition characterized by over-secretion of sweat, most commonly in the underarms and the palms. It can take a heavy toll on those affected, leading to embarrassing social situations and limitation on career mobility. Underarm hyperhidrosis, besides causing wet clothing, can cause skin maceration, skin infections, and unpleasant body odors.

Sweating in hyperhidrosis can arise from different triggers. Localized underarm and palmar hyperhidrosis is usually triggered by emotional stimuli. Generalized hyperhidrosis, with overactive sweating of much of the body, may be associated with certain medical conditions, such as diabetes, hyperthyroidism, and cancer. Therefore, when seeking treatment for excessive sweating, it is important to exclude medical causes of the disorder.

Treatment of hyperhidrosis is varied. Only recently has a low-impact, yet effective treatment become available, in the form of botulinum toxin (Botox). Local treatments for hyperhidrosis include metal salts, such as aluminum chloride. These salts function by plugging up the ducts of the seat glands. This needs to be performed daily at the commencement of treatment, then followed with maintenance regimen once or twice a week. Another method is tap water iontophoresis. The hands or feet are immersed in tap water for 10 minutes while an electric current is applied. The mechanism of action is unknown. Treatments are usually performed several times a week. Surgical treatment is also an option. The sympathetic nerves in the chest can be cut. Finally, the sweat gland-bearing underarm skin can be surgically removed.

Botulinum toxin A (Botox) is a chemical produced by a bacteria, clostridium botulinum. It is the substance found to be responsible for botulism. Botulinum toxin was first used therapeutically in the 1960’s by ophthalmologists, for the treatment of eye muscle disorders. Use of botulinum toxin spread with the treatment of other disorders of muscle spasm. Finally, it was applied cosmetically for the treatment of dynamic facial wrinkles. Simultaneously, it was noted that patients had decreased sweating in areas where botulinum toxin was injected. This led to investigation into its use for hyperhidrosis.

Sweat glands secrete sweat in response to the release of a neurotransmitter, acetylcholine, from nerve endings. Botulinum toxin functions by blocking the release of acetylcholine from the nerve endings. It is not known hoever, whether this is the definitive mechanism of action of botulinum toxin in hyperhidrosis treatment.

Botulinum toxin A, is commercially available as BOTOX in the United States. It is used clinically as follows. Prior to injection, the area of sweating is visualized using the Minor test. First, iodine is applied to the skin and allowed to dry. Corn starch is applied and turns blue in areas where sweating is occurring. The loose starch is then brushed off, allowing one to see where injection is needed. In the underarms, a standard dose of 50 units per side is generally needed and is broken up into smaller aliquots that are injected throughout the involved area. Injection in the underarms is well tolerated and doesn’t require anesthetic. Treatment of the palms and soles, however, is very painful and requires nerve block in the wrist or ankle or the use of topical anesthetic cream.

BOTOX takes effect after approximately 3 days, and is usually maximal after one week. It is approximately 90% effective and generally lasts about 7 months, with a range of 3 to 17 months. In a study by Hornberger et al, mean sweat production at 24 weeks was still below 50% of the preinjection level. 92% of patients were satisfied with the treatment at 4 weeks after injection. Higher doses can somewhat prolong the duration of effect, but at an unacceptably increased cost. Repeat treatments do not lead to the decreased need for BOTOX in the future.

Side effects include those that would be expected from poking the skin with a needle, such as bleeding or infection, although these are uncommon. Rarely, repeated use of botulinum toxin can lead to the development of antibodies to it. This is not harmful but causes the toxin to become ineffective. Use of the toxin in the palm can lead to temporary weakness of hand muscles. Pregnancy, breast feeding, and certain conditions of muscle dysfunction, such as Myasthenia Gravis, are contraindications to the use of botulinum toxin.

In conclusion, when hyperhidrosis causes extreme discomfort or anxiety for an individual, botulinum toxin is the ideal treatment, despite the expense and the need for repeat treatments.

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Excessive underarm sweating is a problem many of us are struggling with. The problem very often starts in the mid or late teens and continues to control our life for years. The embarrassment involved in constant wet and sweaty armpits together with the odour often make us avoid social situations and through this limit the way we live our lives.

Underarm sweating is a problem that is hard to share with your friends and even your family. People tend to think that excessive underarm armpit sweating is a result of bad hygiene and that people who sweat a lot do not shower. Those statements are very often not true.

If you are struggling with excessive armpit sweating you have probably tried every product that is on the market. Anything from different deodorants available in the super-market to the more hardcore antiperspirants they sell at the pharmacy. For most of us those products has little or no effect at all.

A good way to quit your excessive underarm armpit sweating is to use a natural method I was introduced to about a year from now. Unlike the antiperspirants that try to lock up your armpits to stop the sweating to come through, this natural method to stop underarm sweating goes to the root of the problem.

The main reason for sweat is bacteria that are living under your arm. This bacteria actually comes from the soaps and deodorants you use today to get rid of the problem. I am not saying you should not wash your armpits or not use deodorant. I am just telling you that there is a method you can use, that involves cheap and clean products that is available in your local supermarket together with a new way of cleaning your armpits, that will revolutionize your life and stop your excessive armpit sweating problem within a short period of time.

Ones you have taken away all the old medical products you have been using in good faith in the past you are sweating free.

My name is Victor Lorentzo and I got cured for my sweat problems about a year ago. If you want to learn more about the method I used please visit my stop excessive underarm armpit sweating review

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If you are suffering from a sweating problem, such as excessive under arm sweating, then you are not alone. There are thousands of people from all over that suffer from a similar problem with excessive sweating. The sad part of it all is that many of those that have the problem simply suffer in silence, not really seeking an answer to the problem that they have and avoiding the issue rather than facing it to the best of their abilities. So what is it that causes excessive under arm sweating, and is there anything that can be done about it?

Excessive sweating is a condition that is often known as Hyperhidrosis. This problem comes in two different forms, generally speaking. Primary Hyperhidrosis is true Hyperhidrosis, a problem that is generally not understood but has something to do with a problem with the nervous system. This problem causes part of the body to become overactive in the sweat glands, generally a part of the body that has an excess of these glands. The secondary form of Hyperhidrosis is a problem in which an underlying cause will create the sweating problem. This could be anything from an infection or a disease like diabetes or it could be an imbalance of hormones or perhaps a thyroid problem.

The medical community offers little support for those that suffer from excessive underarm sweating. There are some sprays and powders that you can get that will do a little bit of good, and there are even some that come in prescription strength, but for those that truly suffer from the problem these are temporary fixes at best. The real problem will soon show itself through these covers.

Natural methods of curing your overactive sweat glands do exist. In fact you can clear up your sweating problem without using one single drug, cream or other medical treatment. They never really work anyway and provide some temporary relief at best. Visit our website for a special report on how you can finally be free from sweating at http://www.sweat-stop.info/

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Excessive sweating is a health condition that many people suffer from. It is also known as over sweating, profuse sweating as well as extreme sweating and in medical terms is called Hyperhidrosis.

Excessive sweating is something that millions of people suffer from daily and sometimes, something as simple as moving from one room to the other room, can cause a person to sweat uncontrollably. For some people who suffer from excessive sweating, it has become such a problem that they are forced to resort to drastic methods such as surgery or strong medications, to resolve their problems.

Of course this is not always the case, and not all people who suffer from an excessive sweating problem need to use these methods. These people can instead use other methods which are also readily available such as herbal treatments and other holistic remedies. These can include such things as homeopathy, acupuncture and ayurveda.

Not everyone likes to use these types of “exotic” treatments, and for these individuals treatment for their over sweating problem can be found in the arms of more conventional medications and remedies. To find out what these are, you might first want to consult with your physician. You will then be able to get a better picture of what your options are for dealing with the problem of excessive sweating.

Of course, although these methods don’t always work, especially if excessive sweating runs in your family, you can try to control, or rather change, your diet. Sometimes dietary habits can have a larger impact on your body functions than you even realize. Another thing that you might want to look into, and which can also sometimes have a good reaction, is changing your lifestyle somewhat.

More to the point, try to stay as stress free as possible since stress can also bring about excessive sweating. Just think back to the last stress filled situation that you were in, were you not sweating profusely, even though you might not have realized it at the time?

Stress and anxiety-induced over sweating can be controlled more easily than you think, and if you feel that you need help in dealing with this aspect of your life, you can even seek the help of a trained and qualified therapist.

You can of course use commercially available antiperspirants and things, but with the case of excessive sweating these might just not be strong enough to deal with your problem.

Or as mentioned earlier, if your excessive sweating problems are all genetic and passed down to you through your family tree, then help might still be at hand. Ask other members of your family what they did to control their excessive sweating problems. You might find that the answer is lying within your reach!

Are you embarrassed by your sweat stains all over your clothes? You can learn more treatment for excessive sweating naturally now at http://my-sweating.info/

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